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pubmed-article:11372785pubmed:abstractTextTo enhance the stability in vivo, new derivatives of cytogenin were synthesized, and their biological activity and stability in mice were estimated. 2-(8-Hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl)propionic acid (NM-3) was found to be the most stable among them. It modified collagen-induced arthritis in mice. It also showed potent anti-angiogenic activity in a mouse dorsal air sac assay.lld:pubmed
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pubmed-article:11372785pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:11372785pubmed:year2001lld:pubmed
pubmed-article:11372785pubmed:articleTitleSynthesis and biological evaluation of cytogenin derivatives.lld:pubmed
pubmed-article:11372785pubmed:affiliationCentral Research Laboratories, Mercian Corp, Johnan, Fujisawa, Japan. n-matsumoto@hkg.odn.ne.jplld:pubmed
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