Linked Life Data

11345959

Source:http://linkedlifedata.com/resource/pubmed/id/11345959

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-5-10
pubmed:abstractText
This study compared rats with dorsal striatal, ventrolateral prefrontal cortical, and combined lesions of the hippocampus and amygdala to sham controls on a conditional discrimination task in which contextual cues modulated a taste aversion. All groups were able to acquire this occasion setting task. The 2nd experiment functionally minimized the stimulus-response component of the paradigm, creating a "tasteless" form of occasion setting. Rats with pretraining lesions of the hippocampus and amygdala were impaired compared with shams on the acquisition of this tasteless occasion setting task. Rats with posttraining combined lesions did not retain the ability to perform the tasteless occasion setting task learned preoperatively. Rats with selective lesions of either the hippocampus or the amygdala alone were not impaired in the acquisition of the tasteless occasion setting task. The findings suggest that this occasion setting task may be learned by several redundant neural systems.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0735-7044
pubmed:author
pubmed:issnType
Print
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
341-57
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Combined hippocampal and amygdala lesions block learning of a response-independent form of occasion setting.
pubmed:affiliation
Department of Anatomy and Cell Biology, University of Toronto, Ontario, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't