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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2001-4-30
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pubmed:abstractText |
In Alport syndrome (AS) impaired production and/or assembly of col IV alpha-chain isoforms results in abnormal structure of glomerular basement membrane (GBM), haematuria and, frequently, progressive renal disease. We investigated the relationship between col IV alpha-chains expression and morphology of GBM, as a possible key to the better understanding of the pathogenesis of renal disease in AS.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0931-0509
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
945-52
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11328899-Adolescent,
pubmed-meshheading:11328899-Adult,
pubmed-meshheading:11328899-Basement Membrane,
pubmed-meshheading:11328899-Child,
pubmed-meshheading:11328899-Child, Preschool,
pubmed-meshheading:11328899-Collagen,
pubmed-meshheading:11328899-Female,
pubmed-meshheading:11328899-Humans,
pubmed-meshheading:11328899-Immunohistochemistry,
pubmed-meshheading:11328899-Kidney Glomerulus,
pubmed-meshheading:11328899-Male,
pubmed-meshheading:11328899-Microscopy, Electron,
pubmed-meshheading:11328899-Middle Aged,
pubmed-meshheading:11328899-Nephritis, Hereditary,
pubmed-meshheading:11328899-Protein Isoforms,
pubmed-meshheading:11328899-Tissue Distribution
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pubmed:year |
2001
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pubmed:articleTitle |
Distribution of alpha-chains of type IV collagen in glomerular basement membranes with ultrastructural alterations suggestive of Alport syndrome.
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pubmed:affiliation |
Dipartimento di Medicina Sperimentale e Patologia, Università La Sapienza, Viale Regina Elena, 324 (Policlinico Umberto I), I-00161 Rome, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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