Source:http://linkedlifedata.com/resource/pubmed/id/11308995
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2001-4-19
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pubmed:abstractText |
Histocompatible rat strains Lewis (LEW) and Fischer 344 (F344) are often used to study hypothalamic-pituitary-adrenocortical axis function in relation to immune system activity. It has been suggested that LEW rats have a defect in the hypothalamic production of corticotropin-releasing hormone. The aim of this study was to clarify differential responsiveness of LEW and F344 rat strains to acute stress by measuring adrenocorticotropic hormone (ACTH) and corticosterone concentrations in plasma, corticosterone in adrenal cortex and proopiomelanocortin (POMC) gene expression in the pituitary and spleen.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1210-0668
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
35-41
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11308995-Adrenal Cortex,
pubmed-meshheading:11308995-Adrenocorticotropic Hormone,
pubmed-meshheading:11308995-Animals,
pubmed-meshheading:11308995-Corticosterone,
pubmed-meshheading:11308995-Male,
pubmed-meshheading:11308995-Organ Size,
pubmed-meshheading:11308995-Pituitary Gland,
pubmed-meshheading:11308995-Pro-Opiomelanocortin,
pubmed-meshheading:11308995-RNA, Messenger,
pubmed-meshheading:11308995-Rats,
pubmed-meshheading:11308995-Rats, Inbred F344,
pubmed-meshheading:11308995-Rats, Inbred Lew,
pubmed-meshheading:11308995-Restraint, Physical,
pubmed-meshheading:11308995-Spleen,
pubmed-meshheading:11308995-Stress, Physiological
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pubmed:year |
2001
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pubmed:articleTitle |
Differential responses to stress stimuli of Lewis and Fischer rats at the pituitary and adrenocortical level.
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pubmed:affiliation |
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava Slovak Republic. ueenmonc@savba.sk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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