Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2001-4-19
pubmed:abstractText
Histocompatible rat strains Lewis (LEW) and Fischer 344 (F344) are often used to study hypothalamic-pituitary-adrenocortical axis function in relation to immune system activity. It has been suggested that LEW rats have a defect in the hypothalamic production of corticotropin-releasing hormone. The aim of this study was to clarify differential responsiveness of LEW and F344 rat strains to acute stress by measuring adrenocorticotropic hormone (ACTH) and corticosterone concentrations in plasma, corticosterone in adrenal cortex and proopiomelanocortin (POMC) gene expression in the pituitary and spleen.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1210-0668
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
35-41
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Differential responses to stress stimuli of Lewis and Fischer rats at the pituitary and adrenocortical level.
pubmed:affiliation
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava Slovak Republic. ueenmonc@savba.sk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't