Linked Life Data

11306253

Source:http://linkedlifedata.com/resource/pubmed/id/11306253

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2001-4-18
pubmed:abstractText
A major problem of intracellular membrane traffic concerns the way in which transport vesicles find and fuse with their target organelles. SNARE proteins are involved in fusion, and their mutual recognition could in principle provide the necessary specificity. Alternatively, the preliminary tethering of vesicles, mediated by peripheral membrane proteins, could hold the key. Previous studies of SNARE complex assembly in solution have suggested little specificity, but recent experiments with yeast SNAREs anchored in liposomes show that their interactions can be highly selective. It is likely that both tethering and SNARE engagement contribute to the accuracy of membrane transport.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0962-8924
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
99-101
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
SNAREs and the specificity of membrane fusion.
pubmed:affiliation
MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK CB2 2QH. hp@mrc-lmb.ac.uk
pubmed:publicationType
Journal Article, Review