rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2001-4-12
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pubmed:abstractText |
We investigated the association between metamphetamine dependence and TaqI A polymorphism of the dopamine receptor D2 gene (DRD2), I/D polymorphism in angiotensin-converting enzyme (ACE) and M235T polymorphism of the angiotensinogen gene (AGT) in 93 unrelated metamphetamine-dependent subjects and 131 controls. Our results did not prove any association of TaqI A polymorphism of the DRD2 gene, I/D polymorphism of ACE gene, and M235T polymorphism of AGT gene with the metamphetamine dependence in Caucasians of Czech origin. However, a significant difference in allele I frequency between male and female control groups for the I/D ACE polymorphism (p<0.03) was found.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0862-8408
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
43-50
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pubmed:dateRevised |
2008-8-29
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pubmed:meshHeading |
pubmed-meshheading:11300226-Adult,
pubmed-meshheading:11300226-Alleles,
pubmed-meshheading:11300226-Angiotensinogen,
pubmed-meshheading:11300226-Deoxyribonucleases, Type II Site-Specific,
pubmed-meshheading:11300226-Female,
pubmed-meshheading:11300226-Gene Frequency,
pubmed-meshheading:11300226-Genotype,
pubmed-meshheading:11300226-Humans,
pubmed-meshheading:11300226-Male,
pubmed-meshheading:11300226-Methamphetamine,
pubmed-meshheading:11300226-Peptidyl-Dipeptidase A,
pubmed-meshheading:11300226-Polymerase Chain Reaction,
pubmed-meshheading:11300226-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:11300226-Receptors, Dopamine D2,
pubmed-meshheading:11300226-Sex Characteristics,
pubmed-meshheading:11300226-Substance-Related Disorders
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pubmed:year |
2001
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pubmed:articleTitle |
The association study of DRD2, ACE and AGT gene polymorphisms and metamphetamine dependence.
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pubmed:affiliation |
Department of Comparative Animal Physiology and General Zoology, Masaryk University, Faculty of Science, Brno, Czech Republic. omarsery@sci.muni.cz
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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