Source:http://linkedlifedata.com/resource/pubmed/id/11292216
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2001-4-6
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pubmed:abstractText |
Over the last several years, botulinum toxin type A has gained widespread use for the management of focal spasticity in children with cerebral palsy. To assess the current patterns of botulinum toxin type A use in the clinical setting, the dose, muscles injected, age at injection, and interval between injections of botulinum toxin type A treatments were examined in a retrospective chart review of children with cerebral palsy (N = 270) over a 2-year period at three major treatment centers. The average dose of botulinum toxin type A across the three centers ranged from 7.7 to 10.8 U/kg body weight, and the average total amount of botulinum toxin type A injected at a single visit ranged from 154 to 205 U. The majority of botulinum toxin type A injections were to the muscles to the lower limbs. The average age at first injection was 6.2 years, and the average interval between injections ranged from 134 to 199 days.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0883-0738
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
113-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:11292216-Adolescent,
pubmed-meshheading:11292216-Botulinum Toxins, Type A,
pubmed-meshheading:11292216-Cerebral Palsy,
pubmed-meshheading:11292216-Child,
pubmed-meshheading:11292216-Child, Preschool,
pubmed-meshheading:11292216-Clinical Protocols,
pubmed-meshheading:11292216-Dose-Response Relationship, Drug,
pubmed-meshheading:11292216-Female,
pubmed-meshheading:11292216-Humans,
pubmed-meshheading:11292216-Infant,
pubmed-meshheading:11292216-Injections, Intramuscular,
pubmed-meshheading:11292216-Male,
pubmed-meshheading:11292216-Medical Records,
pubmed-meshheading:11292216-Neuromuscular Agents,
pubmed-meshheading:11292216-Retrospective Studies,
pubmed-meshheading:11292216-Treatment Outcome
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pubmed:year |
2001
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pubmed:articleTitle |
Use of botulinum toxin type A in pediatric patients with cerebral palsy: a three-center retrospective chart review.
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pubmed:affiliation |
Department of Physical Medicine and Rehabilitation, Gillette Children's Specialty Healthcare, St. Paul, MN 55101, USA. mgormley@gillettechildrens.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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