Source:http://linkedlifedata.com/resource/pubmed/id/11275813
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2001-3-29
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pubmed:abstractText |
We describe two patients who developed multiple itching nodules following immunization with vaccines adsorbed on aluminium hydroxide. Both patients had been treated with vaccines for extrinsic asthma and rhinitis for 4 and 10 years respectively. The lesions were persistent and lasted for several years. Histopathological findings were those of a foreign body reaction. Aluminium was most probably involved in the pathogenesis of these lesions because its presence could be demonstrated in macrophages using energy-dispersive X-ray microanalysis. Although some symptomatic relief was achieved with topical corticosteroids and oral antihistamines, treatment was unsuccessful.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1167-1122
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
138-40
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11275813-Adult,
pubmed-meshheading:11275813-Allergens,
pubmed-meshheading:11275813-Aluminum Hydroxide,
pubmed-meshheading:11275813-Arm,
pubmed-meshheading:11275813-Asthma,
pubmed-meshheading:11275813-Desensitization, Immunologic,
pubmed-meshheading:11275813-Drug Eruptions,
pubmed-meshheading:11275813-Female,
pubmed-meshheading:11275813-Foreign-Body Reaction,
pubmed-meshheading:11275813-Humans,
pubmed-meshheading:11275813-Injections, Subcutaneous,
pubmed-meshheading:11275813-Patch Tests,
pubmed-meshheading:11275813-Rhinitis
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pubmed:articleTitle |
Subcutaneous nodules following treatment with aluminium-containing allergen extracts.
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pubmed:affiliation |
Department of Dermatology, Hospital General Universitario, C/Denia, 20-6a, 46006 Valencia, Spain.
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pubmed:publicationType |
Journal Article,
Case Reports
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