Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2001-3-29
pubmed:abstractText
The conversion of light to chemical energy by the process of photosynthesis is localized to the thylakoid membrane network in plant chloroplasts. Although several pathways have been described that target proteins into and across the thylakoids, little is known about the origin of this membrane system or how the lipid backbone of the thylakoids is transported and fused with the target membrane. Thylakoid biogenesis and maintenance seem to involve the flow of membrane elements via vesicular transport. Here we show by mutational analysis that deletion of a single gene called VIPP1 (vesicle-inducing protein in plastids 1) is deleterious to thylakoid membrane formation. Although VIPP1 is a hydrophilic protein it is found in both the inner envelope and the thylakoid membranes. In VIPP1 deletion mutants vesicle formation is abolished. We propose that VIPP1 is essential for the maintenance of thylakoids by a transport pathway not previously recognized.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-10213778, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-11274378, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-11274448, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-1547267, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-16668584, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-1712397, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-7777561, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-8061316, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-8389965, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-8717135, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-8905231, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-9261050, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-9378616, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-9463364, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-9484595, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-9736608, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-9738967, http://linkedlifedata.com/resource/pubmed/commentcorrection/11274447-9861056
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:day
27
pubmed:volume
98
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4238-42
pubmed:dateRevised
2010-9-14
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
VIPP1, a nuclear gene of Arabidopsis thaliana essential for thylakoid membrane formation.
pubmed:affiliation
Institut für Entwicklungs- und Molekularbiologie der Pflanzen, Heinrich-Heine-Universität, Universitätsstrasse 1, 40225 Düsseldorf, Germany.
pubmed:publicationType
Journal Article, Comment, Research Support, Non-U.S. Gov't