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rdf:type |
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lifeskim:mentions |
umls-concept:C0004057,
umls-concept:C0023516,
umls-concept:C0086418,
umls-concept:C0205332,
umls-concept:C0596290,
umls-concept:C0699795,
umls-concept:C1261512,
umls-concept:C1304680,
umls-concept:C1515654,
umls-concept:C1522318,
umls-concept:C1532563
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pubmed:issue |
12
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|
pubmed:dateCreated |
2001-3-29
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pubmed:abstractText |
Leukocyte attack (LA) and the triggered reactive proliferation of smooth muscle cells (SMCs) are key events for the development of early atherosclerosis and restenosis. In the present study, we used a 3D human coronary in vitro model of LA (3DLA model) to examine the effect of high-dose aspirin on the adhesion and chemotaxis of leukocytes and the reactive proliferative response of SMCs.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
27
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1688-94
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11273998-Aspirin,
pubmed-meshheading:11273998-Blotting, Northern,
pubmed-meshheading:11273998-Bromodeoxyuridine,
pubmed-meshheading:11273998-CD4-Positive T-Lymphocytes,
pubmed-meshheading:11273998-Cell Adhesion,
pubmed-meshheading:11273998-Cell Division,
pubmed-meshheading:11273998-Cells, Cultured,
pubmed-meshheading:11273998-Chemotaxis,
pubmed-meshheading:11273998-Coronary Artery Disease,
pubmed-meshheading:11273998-Dose-Response Relationship, Drug,
pubmed-meshheading:11273998-Endothelium, Vascular,
pubmed-meshheading:11273998-Flow Cytometry,
pubmed-meshheading:11273998-Humans,
pubmed-meshheading:11273998-Intercellular Adhesion Molecule-1,
pubmed-meshheading:11273998-Leukocytes,
pubmed-meshheading:11273998-Monocytes,
pubmed-meshheading:11273998-Muscle, Smooth, Vascular,
pubmed-meshheading:11273998-RNA, Messenger,
pubmed-meshheading:11273998-Tumor Necrosis Factor-alpha
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pubmed:year |
2001
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pubmed:articleTitle |
Aspirin (5 mmol/L) inhibits leukocyte attack and triggered reactive cell proliferation in a 3D human coronary in vitro model.
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pubmed:affiliation |
Department of Internal Medicine II, Division of Cardiology, University of Ulm, Germany. rainer.voisard@medizin.uni-ulm.de
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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