Source:http://linkedlifedata.com/resource/pubmed/id/11256009
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2001-3-20
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pubmed:abstractText |
Amiodarone is useful for the treatment of ventricular and supraventricular arrhythmias, but it has been associated with several adverse effects. Amiodarone-induced hepatotoxicity is a frequent complication and often consist in a mild and asymptomatic elevation of liver function tests, although severe cases have been described. A case of severe amiodarone-induced hepatotoxicity slowly resolving after discontinuation of the drug and in which liver biopsy was crucial for diagnosis is reported. Although there are no pathognomonic histopathological findings, phospholipidosis is the morphologic hallmark of amiodarone hepatotoxicity.
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pubmed:language |
spa
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0556-6177
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
86-91
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11256009-Aged,
pubmed-meshheading:11256009-Amiodarone,
pubmed-meshheading:11256009-Anti-Arrhythmia Agents,
pubmed-meshheading:11256009-Drug-Induced Liver Injury,
pubmed-meshheading:11256009-Heart Block,
pubmed-meshheading:11256009-Humans,
pubmed-meshheading:11256009-Liver,
pubmed-meshheading:11256009-Liver Diseases,
pubmed-meshheading:11256009-Male
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pubmed:articleTitle |
[Severe hepatotoxicity caused by amiodarone: description of a case].
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pubmed:affiliation |
Departamento de Medicina Interna, Unidad de Hepatología, Clínica Universitaria, Facultad de Medicina, Universidad de Navarra.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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