Source:http://linkedlifedata.com/resource/pubmed/id/11245725
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2001-3-14
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pubmed:abstractText |
The association between aldosterone synthase (CYP11B2) gene polymorphism and white matter hyperintensities seen on cerebral MRI was studied in a population-based sample of 829 individuals aged 63 to 75 years. The T allele was associated with the risk of severe white matter hyperintensities. Compared with the CC genotype, the adjusted OR for severe white matter hyperintensities was 4.61 (95% CI, 1.46 to 14.55) for the TT genotype and 2.45 (95% CI, 0.81 to 7.46) for the TC genotype in men. This association was independent of hypertension.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0028-3878
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
13
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
673-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11245725-Aged,
pubmed-meshheading:11245725-Aldosterone Synthase,
pubmed-meshheading:11245725-Blood Pressure,
pubmed-meshheading:11245725-Brain Diseases,
pubmed-meshheading:11245725-Female,
pubmed-meshheading:11245725-Genotype,
pubmed-meshheading:11245725-Humans,
pubmed-meshheading:11245725-Male,
pubmed-meshheading:11245725-Middle Aged,
pubmed-meshheading:11245725-Polymorphism, Genetic
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pubmed:year |
2001
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pubmed:articleTitle |
Aldosterone synthase (CYP11B2) gene polymorphism and cerebral white matter hyperintensities.
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pubmed:affiliation |
Institut National de la Santé et de la Recherche Médicale U360, Hôpital Pitié-Salpêtrière, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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