Linked Life Data

11243197

Source:http://linkedlifedata.com/resource/pubmed/id/11243197

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-3-12
pubmed:abstractText
Based on two major factors resulted in adult respiratory distress syndrome (ARDS), lack of pulmonary surfactant and damage of free radicals, an artificial reconstituted pulmonary surfactant (APS) was prepared. The results of prevention of ARDS in ARDS rats showed that APS reduced the mortality of animal model significantly (from 46.47% to 16.17%) and the ratio of wet/dry lung weight (from 5.55 to 4.84). The surface properties of lung lavage of treated animals were improved effectively [balancing surface tension from 61.86 mN.m-1 to 47.02 mN.m-1, (normal 43.94 mN.m-1), minimal surface tension from 30.41 mN.m-1 to 7.16 mN.m-1(normal 3.49 mN.m-1)]. These results indicate that the APS preparation showed better effect on prevention of ARDS in rats.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0513-4870
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
127-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
[Artificial reconstituted pulmonary surfactant used for prevention and treatment of adult respiratory distress syndrome. III. Prevention in animal model].
pubmed:affiliation
Division of Biopharmaceutics, School of Pharmacy, Shanghai Medical University, Shanghai 200032.
pubmed:publicationType
Journal Article, English Abstract