Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2001-3-12
pubmed:abstractText
Little is known about the epidemiology of human herpesvirus 8 (HHV-8) infections among women. A cross-sectional study was conducted of HHV-8 infection among human immunodeficiency virus (HIV)-infected and high-risk HIV-uninfected women. Serological tests with noninduced (latent) and induced (lytic) HHV-8 antigens were used to detect infection among 2483 participants of a multisite cohort. Reactivity to latent antigen was present in 4.1% and to induced antigens in 12.0% of women. Seven of 8 women who reported Kaposi's sarcoma had HHV-8 antibodies. Among HIV-positive women, HHV-8 infection was associated with use of crack, cocaine, or heroin (76% vs. 65%; P<.001), past syphilis (29% vs. 20%; P<.001), an injection drug-using male sex partner (61% vs. 53%; P=.014), black race (P=.010), and enrollment site (P=.015). In multivariate analysis, HIV infection, older age, past syphilis, black race, and enrollment site were independently associated with HHV-8 infection. In this cohort of North American women, HHV-8 infection was associated with HIV infection, drug use, and risky sexual behavior.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-1899
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
183
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1130-4
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:11237842-Adult, pubmed-meshheading:11237842-Antibodies, Viral, pubmed-meshheading:11237842-California, pubmed-meshheading:11237842-Cocaine, pubmed-meshheading:11237842-Cohort Studies, pubmed-meshheading:11237842-Crack Cocaine, pubmed-meshheading:11237842-Cross-Sectional Studies, pubmed-meshheading:11237842-District of Columbia, pubmed-meshheading:11237842-Female, pubmed-meshheading:11237842-HIV Infections, pubmed-meshheading:11237842-HIV Seronegativity, pubmed-meshheading:11237842-HIV Seropositivity, pubmed-meshheading:11237842-Heroin, pubmed-meshheading:11237842-Herpesviridae Infections, pubmed-meshheading:11237842-Herpesvirus 8, Human, pubmed-meshheading:11237842-Humans, pubmed-meshheading:11237842-New York, pubmed-meshheading:11237842-Prevalence, pubmed-meshheading:11237842-Risk Factors, pubmed-meshheading:11237842-Sarcoma, Kaposi, pubmed-meshheading:11237842-Seroepidemiologic Studies, pubmed-meshheading:11237842-Sex Factors, pubmed-meshheading:11237842-Substance Abuse, Intravenous, pubmed-meshheading:11237842-Syphilis
pubmed:year
2001
pubmed:articleTitle
Human herpesvirus 8 infection and Kaposi's sarcoma among human immunodeficiency virus-infected and -uninfected women.
pubmed:affiliation
University of California, San Francisco, Infectious Diseases Division, San Francisco, CA 94122, USA. ruthg@itsa.ucsf.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.