Source:http://linkedlifedata.com/resource/pubmed/id/11213284
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2001-2-12
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pubmed:abstractText |
Quinolactacins A (1), B (2) and C (3), novel quinolone antibiotics have been found from the cultured broth of a fungal strain isolated from the larvae of the mulberry pyralid Margaronia pyloalis Welker). The fungal strain, EPF-6 was identified as Penicillium sp. from its morphological characteristics. Quinolactacins were obtained from the culture medium by solvent extraction and chromatographic purification. Compound 1 showed inhibitory activity against tumor necrosis factor (TNF) production induced by murine peritoneal macrophages and macrophage-like J774.1 cells stimulated with lipopolysaccharide (LPS).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0021-8820
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1247-51
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11213284-Animals,
pubmed-meshheading:11213284-Anti-Bacterial Agents,
pubmed-meshheading:11213284-Female,
pubmed-meshheading:11213284-Fermentation,
pubmed-meshheading:11213284-Macrophages, Peritoneal,
pubmed-meshheading:11213284-Mice,
pubmed-meshheading:11213284-Mice, Inbred C3H,
pubmed-meshheading:11213284-Microbial Sensitivity Tests,
pubmed-meshheading:11213284-Microscopy, Electron, Scanning,
pubmed-meshheading:11213284-Molecular Structure,
pubmed-meshheading:11213284-Penicillium,
pubmed-meshheading:11213284-Quinolones,
pubmed-meshheading:11213284-Tumor Necrosis Factor-alpha
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pubmed:year |
2000
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pubmed:articleTitle |
Quinolactacins A, B and C: novel quinolone compounds from Penicillium sp. EPF-6. I. Taxonomy, production, isolation and biological properties.
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pubmed:affiliation |
United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology, Fuchu, Japan.
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pubmed:publicationType |
Journal Article
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