Source:http://linkedlifedata.com/resource/pubmed/id/11211613
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2001-2-9
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pubmed:abstractText |
Eosinophilic angiocentric fibrosis (EAF) is a rare submucosal fibrosis without a well-developed differential diagnosis. Three cases of sinonasal tract EAF were identified in 2 women and 1 man, aged 49, 64, and 28 years, respectively. The patients experienced a nasal cavity mass, maxillary pain, or nasal obstructive symptoms of long duration. The process involved the nasal septum (n = 2), nasal cavity (n = 1), and/or the maxillary sinus (n = 1). There was no evidence for Wegener granulomatosis, Churg-Strauss syndrome, Kimura disease, granuloma faciale, or erythema elevatum diutinum. Histologically, the lesions demonstrated a characteristic perivascular "onion-skin" fibrosis and a full spectrum of inflammatory cells, although eosinophils predominated. Necrosis and foreign body-type giant cells were not identified. Surgical excision was used for all patients, who are all alive but with disease at last follow-up. Sinonasal tract EAF is a unique fibroproliferative disorder that does not seem to have systemic associations with known diseases. The characteristic histomorphologic features permit accurate diagnosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0002-9173
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
115
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
243-8
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:11211613-Adult,
pubmed-meshheading:11211613-Biological Markers,
pubmed-meshheading:11211613-Eosinophilia,
pubmed-meshheading:11211613-Female,
pubmed-meshheading:11211613-Fibrosis,
pubmed-meshheading:11211613-Humans,
pubmed-meshheading:11211613-Immunohistochemistry,
pubmed-meshheading:11211613-Male,
pubmed-meshheading:11211613-Middle Aged,
pubmed-meshheading:11211613-Nasal Obstruction,
pubmed-meshheading:11211613-Nose Diseases,
pubmed-meshheading:11211613-Paranasal Sinuses
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pubmed:year |
2001
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pubmed:articleTitle |
Sinonasal tract eosinophilic angiocentric fibrosis. A report of three cases.
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pubmed:affiliation |
Department of Endocrine and Otorhinolaryngic-Head & Neck Pathology, Armed Forces Institute of Pathology, 6825 16th St, NW, Washington, DC 20306-6000, USA.
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pubmed:publicationType |
Journal Article,
Review,
Case Reports
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