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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2001-3-6
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pubmed:abstractText |
The optimal strategy for the detection of hereditary nonpolyposis colorectal cancer (HNPCC) gene carriers remains uncertain. We evaluated whether microsatellite instability (MSI) analysis or MSH2 and MLH1 protein immunostaining of tumors will screen individuals efficiently for germline MSH2 and MLH1 testing.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:ConradP GPG,
pubmed-author:CrawleyS CSC,
pubmed-author:HepburnMM,
pubmed-author:KimY SYS,
pubmed-author:LewisS YSY,
pubmed-author:MillerG AGA,
pubmed-author:NgRR,
pubmed-author:ReevesCC,
pubmed-author:SchmittAA,
pubmed-author:SleisengerM HMH,
pubmed-author:TerdimanJ PJP,
pubmed-author:WeinbergVV
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pubmed:issnType |
Print
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pubmed:volume |
120
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
21-30
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11208710-Colorectal Neoplasms, Hereditary Nonpolyposis,
pubmed-meshheading:11208710-DNA Mutational Analysis,
pubmed-meshheading:11208710-DNA-Binding Proteins,
pubmed-meshheading:11208710-Family Health,
pubmed-meshheading:11208710-Genetic Predisposition to Disease,
pubmed-meshheading:11208710-Genetic Testing,
pubmed-meshheading:11208710-Germ-Line Mutation,
pubmed-meshheading:11208710-Humans,
pubmed-meshheading:11208710-Immunohistochemistry,
pubmed-meshheading:11208710-Microsatellite Repeats,
pubmed-meshheading:11208710-MutS Homolog 2 Protein,
pubmed-meshheading:11208710-Predictive Value of Tests,
pubmed-meshheading:11208710-Proteins,
pubmed-meshheading:11208710-Proto-Oncogene Proteins
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pubmed:year |
2001
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pubmed:articleTitle |
Efficient detection of hereditary nonpolyposis colorectal cancer gene carriers by screening for tumor microsatellite instability before germline genetic testing.
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pubmed:affiliation |
Department of Medicine, University of California, San Francisco, San Francisco, California, USA. jterd@itsa.ucsf.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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