| pubmed-article:11206471 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11206471 | lifeskim:mentions | umls-concept:C0032433 | lld:lifeskim |
| pubmed-article:11206471 | lifeskim:mentions | umls-concept:C0041214 | lld:lifeskim |
| pubmed-article:11206471 | lifeskim:mentions | umls-concept:C0679932 | lld:lifeskim |
| pubmed-article:11206471 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:11206471 | lifeskim:mentions | umls-concept:C1704419 | lld:lifeskim |
| pubmed-article:11206471 | lifeskim:mentions | umls-concept:C0077419 | lld:lifeskim |
| pubmed-article:11206471 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:11206471 | pubmed:dateCreated | 2001-2-5 | lld:pubmed |
| pubmed-article:11206471 | pubmed:abstractText | Several N-(3-phenylpropyl)-substituted spermidine and spermine derivatives were prepared and found to be potent competitive inhibitors of Trypanosoma cruzi trypanothione reductase (seven compounds with Ki values < 5 microM are described). The most effective inhibitor studied was compound 12 with a Ki value of 0.151 microM. Six of the compounds described are also effective trypanocides with IC50 values < 1 microM. | lld:pubmed |
| pubmed-article:11206471 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11206471 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11206471 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:11206471 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11206471 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11206471 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:11206471 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:11206471 | pubmed:author | pubmed-author:BacchiC JCJ | lld:pubmed |
| pubmed-article:11206471 | pubmed:author | pubmed-author:MASS | lld:pubmed |
| pubmed-article:11206471 | pubmed:author | pubmed-author:GanemBB | lld:pubmed |
| pubmed-article:11206471 | pubmed:author | pubmed-author:O'SullivanM... | lld:pubmed |
| pubmed-article:11206471 | pubmed:author | pubmed-author:RattendiDD | lld:pubmed |
| pubmed-article:11206471 | pubmed:author | pubmed-author:FennieM WMW | lld:pubmed |
| pubmed-article:11206471 | pubmed:author | pubmed-author:HancockM TMT | lld:pubmed |
| pubmed-article:11206471 | pubmed:author | pubmed-author:KobaslijaMM | lld:pubmed |
| pubmed-article:11206471 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11206471 | pubmed:day | 22 | lld:pubmed |
| pubmed-article:11206471 | pubmed:volume | 11 | lld:pubmed |
| pubmed-article:11206471 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11206471 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11206471 | pubmed:pagination | 251-4 | lld:pubmed |
| pubmed-article:11206471 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:11206471 | pubmed:meshHeading | pubmed-meshheading:11206471... | lld:pubmed |
| pubmed-article:11206471 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11206471 | pubmed:articleTitle | Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents. | lld:pubmed |
| pubmed-article:11206471 | pubmed:affiliation | Department of Chemistry, Indiana State University, Terre Haute 47809, USA. | lld:pubmed |
| pubmed-article:11206471 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11206471 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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