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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1975-5-29
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pubmed:abstractText |
In Zollinger-Ellison patients the gastric mucosa is characterized histologically by hyperplasia both of the glands and the gastric pits. The fundic gastric mucosa is thickened with a marked increase of the specific glandular cells. In-vitro autoradiographic examination shows a significant increase in proliferation of the stomach epithelial cells in three patients with hypergastrinaemia. The mean generation time was diminished from 72 plus or minus 2 in controls to 45 plus or minus 4 hours in the Zollinger-Ellison patients owing to a reduction of the G-1 phase from 62-63 to 36-37 hours. The labelling index (3-H-index) was increased from 10.0 plus or minus 0.2 to 15.7 plus or minus 1.8%. The DNA synthesis phase, the G-2 phase, and the mitotic time were not altered compared to the controls.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0300-970X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
40-3
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1119303-Adult,
pubmed-meshheading:1119303-Autoradiography,
pubmed-meshheading:1119303-Cell Division,
pubmed-meshheading:1119303-Female,
pubmed-meshheading:1119303-Gastric Mucosa,
pubmed-meshheading:1119303-Humans,
pubmed-meshheading:1119303-Male,
pubmed-meshheading:1119303-Middle Aged,
pubmed-meshheading:1119303-Regeneration,
pubmed-meshheading:1119303-Zollinger-Ellison Syndrome
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pubmed:year |
1975
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pubmed:articleTitle |
Cell renewal of gastric mucosa in Zollinger-Ellison syndrome.
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pubmed:publicationType |
Journal Article
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