rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1975-5-27
|
pubmed:abstractText |
Rats were fed a 5 or 20% casein diet that causes liver necrosis unless supplemented with vitamin E or selenite. The following activities were studied in liver subcellar fractions: enzymic formation of lipid peroxides, NADPH-cytochrome c reductase, oxidative demethylation of aminopyrine, and incorporation of [14C]leucine into protein (with microsomes); xanthine oxidase (with soluble supernatant); and RNA polymerases I and II (with nuclei). Formation of lipid peroxides was higher in rats fed diets without vitamin E and was not reduced significantly by dietary selenite. The activity of xanthine oxidase was higher in animals fed the 20% casein than in those fed the 5% casein diet; however, a higher activity was observed in the rats fed the latter diet without vitamin E or selenite than in those receiving these supplements. The activity of RNA polymerase I was higher in rats fed the low casein diet. Other activities examined were not affected significantly by the level of dietary casein or by vitamin E or selenits.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0022-3166
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
105
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
364-71
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1117348-Aminopyrine N-Demethylase,
pubmed-meshheading:1117348-Animals,
pubmed-meshheading:1117348-Cell Nucleus,
pubmed-meshheading:1117348-Cytochrome Reductases,
pubmed-meshheading:1117348-DNA-Directed RNA Polymerases,
pubmed-meshheading:1117348-Dietary Proteins,
pubmed-meshheading:1117348-Lipid Metabolism,
pubmed-meshheading:1117348-Liver,
pubmed-meshheading:1117348-Male,
pubmed-meshheading:1117348-Microsomes, Liver,
pubmed-meshheading:1117348-Peroxides,
pubmed-meshheading:1117348-Protein Biosynthesis,
pubmed-meshheading:1117348-Rats,
pubmed-meshheading:1117348-Selenium,
pubmed-meshheading:1117348-Vitamin E Deficiency,
pubmed-meshheading:1117348-Xanthine Oxidase
|
pubmed:year |
1975
|
pubmed:articleTitle |
Studies on the formation of lipid peroxides and on some enzymic activities in the liver of vitamin E-deficient rats.
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pubmed:publicationType |
Journal Article
|