Source:http://linkedlifedata.com/resource/pubmed/id/11169056
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2001-1-19
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pubmed:abstractText |
Combination therapy with interferon alpha (IFNalpha) plus ribavirin has been shown to improve the sustained response rate in patients with chronic hepatitis C but there is little information regarding the lengths of time for this therapeutic regimen. In this study we therefore tried to evaluate whether the analysis of different virological parameters could provide new clues with respect to the early determination of the efficacy of this form of combination therapy. Furthermore, we also examined whether short-term induction combination therapy followed by IFNalpha alone is more effective than monotherapy in mounting an initial as well as a sustained virological response.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0106-9543
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
427-36
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11169056-Adult,
pubmed-meshheading:11169056-Aged,
pubmed-meshheading:11169056-Antiviral Agents,
pubmed-meshheading:11169056-Drug Therapy, Combination,
pubmed-meshheading:11169056-Female,
pubmed-meshheading:11169056-Hepacivirus,
pubmed-meshheading:11169056-Hepatitis C, Chronic,
pubmed-meshheading:11169056-Humans,
pubmed-meshheading:11169056-Interferon-alpha,
pubmed-meshheading:11169056-Male,
pubmed-meshheading:11169056-Middle Aged,
pubmed-meshheading:11169056-Prospective Studies,
pubmed-meshheading:11169056-RNA, Viral,
pubmed-meshheading:11169056-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:11169056-Ribavirin,
pubmed-meshheading:11169056-Time Factors,
pubmed-meshheading:11169056-Treatment Outcome,
pubmed-meshheading:11169056-Viremia
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pubmed:year |
2000
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pubmed:articleTitle |
Efficacy of a short-term ribavirin plus interferon alpha combination therapy followed by interferon alpha alone in previously untreated patients with chronic hepatitis C: a randomized multicenter trial.
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pubmed:affiliation |
Medizinische Klinik mit Schwerpunkt, Hepatologie und Gastroenterologie, Universitätsklinikum Charité, Humboldt-Universität, Berlin, Germany. thomas.berg@charite.de
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Multicenter Study
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