|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007589,
umls-concept:C0007634,
umls-concept:C0023470,
umls-concept:C0034284,
umls-concept:C0086418,
umls-concept:C0205263,
umls-concept:C0205314,
umls-concept:C0243072,
umls-concept:C0679622,
umls-concept:C1511938,
umls-concept:C1883254
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|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2001-2-22
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|
pubmed:abstractText |
Some pyrimidine analogues have been found to induce differentiation of several human myeloid leukemia cells. Newly synthesized heterocyclic pyrimidine derivatives promote neurite outgrowth and survival in neuronal cell lines. In this study, the growth-inhibiting and differentiation-inducing effects of these pyrimidine derivatives on human myeloid leukemia cells were examined.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0301-472X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
29
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
194-201
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|
pubmed:dateRevised |
2009-11-19
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|
pubmed:meshHeading |
pubmed-meshheading:11166458-Calcitriol,
pubmed-meshheading:11166458-Cell Differentiation,
pubmed-meshheading:11166458-Cell Division,
pubmed-meshheading:11166458-Enzyme Activation,
pubmed-meshheading:11166458-Enzyme Inhibitors,
pubmed-meshheading:11166458-Flavonoids,
pubmed-meshheading:11166458-Granulocytes,
pubmed-meshheading:11166458-HL-60 Cells,
pubmed-meshheading:11166458-Humans,
pubmed-meshheading:11166458-Leukemia, Erythroblastic, Acute,
pubmed-meshheading:11166458-Leukemia, Myeloid,
pubmed-meshheading:11166458-Mitogen-Activated Protein Kinases,
pubmed-meshheading:11166458-Monocytes,
pubmed-meshheading:11166458-Nitroblue Tetrazolium,
pubmed-meshheading:11166458-Pyrimidines,
pubmed-meshheading:11166458-Tretinoin,
pubmed-meshheading:11166458-Tumor Cells, Cultured
|
|
pubmed:year |
2001
|
|
pubmed:articleTitle |
Induction of differentiation of human myeloid leukemia cells by novel synthetic neurotrophic pyrimidine derivatives.
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|
pubmed:affiliation |
Saitama Cancer Center Research Institute, Ina, Saitama, Japan. honma@cancer-c.pref.saitama.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
