Source:http://linkedlifedata.com/resource/pubmed/id/11165120
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2001-2-22
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| pubmed:abstractText |
Of the 16,024 patients hospitalized from January 1995 to October 1997, 397 (2.4%) acquired nosocomial pneumonia and the aetiological agent was defined in 101 (25%). About 82% developed late onset pneumonia (>7 days of hospitalization). The site of isolation of microorganisms was bronchoalveolar lavage (BAL) (49%), blood culture (39%), pleural effusion (10%) and (2%) pulmonary tissue. Gram-negative bacteria were responsible for 54% of infections. Staphylococcus aureus (34%) was the most frequent microorganism isolated followed by Acinetobacter baumannii (29%) and Pseudomonas aeruginosa and Klebsiella pneumoniae, responsible for 7% of nosocomial pneumonia. Monotherapy gave good cover for early onset pneumonia, but not for late onset pneumonia. Based on our selection criteria, ciprofloxacin was the best monotherapy for early (50%) and late (31%) onset pneumonia. Vancomycin plus ciprofloxacin gave cover of 85% of early and 64% of late onset pneumonia. Monotherapy with ciprofloxacin and also combination therapy of ciprofloxacin plus vancomycin may be good options as initial empirical therapy for nosocomial pneumonia.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
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| pubmed:issn |
0924-8579
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
17
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
147-50
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| pubmed:dateRevised |
2005-11-17
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| pubmed:meshHeading |
pubmed-meshheading:11165120-Anti-Bacterial Agents,
pubmed-meshheading:11165120-Bacteria,
pubmed-meshheading:11165120-Blood,
pubmed-meshheading:11165120-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:11165120-Ciprofloxacin,
pubmed-meshheading:11165120-Cross Infection,
pubmed-meshheading:11165120-Drug Therapy, Combination,
pubmed-meshheading:11165120-Humans,
pubmed-meshheading:11165120-Lung,
pubmed-meshheading:11165120-Pleural Effusion,
pubmed-meshheading:11165120-Pneumonia, Bacterial,
pubmed-meshheading:11165120-Vancomycin
|
| pubmed:year |
2001
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| pubmed:articleTitle |
Nosocomial pneumonia: importance of recognition of aetiological agents to define an appropriate initial empirical therapy.
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| pubmed:affiliation |
Nosocomial Infection Control Group, Hospital das Clínicas, University of São Paulo, HC-FMUSP, Avenida Dr Eneas Carvalho de Aguiar 255, SP, São Paulo, Brazil. gcih@hcnet.usp.br
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| pubmed:publicationType |
Journal Article
|