Source:http://linkedlifedata.com/resource/pubmed/id/11153590
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2001-1-10
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| pubmed:abstractText |
The aim of the study was to compare the lung sounds in patients with asbestos related pulmonary disorders with findings in high-resolution computed tomography (HRCT), and with lung function variables, in order to find out associations of acoustic changes with radiological fibrosis, emphysema or with pulmonary gas transfer functions. Sixty-four patients with asbestos-related pleural disease, with or without pulmonary disease, were studied. Lung sound recording and analysis was carried out with a computerized lung sound analyser, and HRCT of the chest, as well as forced spirometry and diffusing capacity measurement were performed. The fibrosis score correlated positively with the quartile frequencies of the power spectrum of lung sounds in inspiration (f50) and expiration (f50) and crackle count in inspiration, as well as negatively with diffusing capacity. When the patients with crackling sounds and significant fibrosis were excluded (n=18), emphysema correlated negatively with expiratory quartile frequencies of the power spectrum, with f25 and f50. Furthermore, diffusing capacity correlated with inspiratory f25 and forced expiratory volume in one second with inspiratory f50 when crackles and fibrosis were excluded. Changes in lung sounds were significantly associated with radiologically verified abnormalities and gas transfer of pulmonary tissue. High sound frequencies were associated with fibrotic changes of the lung while low sound frequencies with pulmonary emphysema. Acoustic analysis gives complementary clinical information for evaluation of asbestos-related pulmonary disorders.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
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| pubmed:issn |
0903-1936
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
16
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
901-8
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:11153590-Aged,
pubmed-meshheading:11153590-Asbestos,
pubmed-meshheading:11153590-Body Mass Index,
pubmed-meshheading:11153590-Environmental Exposure,
pubmed-meshheading:11153590-Humans,
pubmed-meshheading:11153590-Lung,
pubmed-meshheading:11153590-Lung Diseases,
pubmed-meshheading:11153590-Male,
pubmed-meshheading:11153590-Middle Aged,
pubmed-meshheading:11153590-Pleura,
pubmed-meshheading:11153590-Pulmonary Diffusing Capacity,
pubmed-meshheading:11153590-Pulmonary Emphysema,
pubmed-meshheading:11153590-Pulmonary Fibrosis,
pubmed-meshheading:11153590-Pulmonary Gas Exchange,
pubmed-meshheading:11153590-Radiography, Thoracic,
pubmed-meshheading:11153590-Respiratory Function Tests,
pubmed-meshheading:11153590-Respiratory Sounds,
pubmed-meshheading:11153590-Tomography, X-Ray Computed
|
| pubmed:year |
2000
|
| pubmed:articleTitle |
Lung sounds in asbestos induced pulmonary disorders.
|
| pubmed:affiliation |
Dept of Occupational Diseases, Finnish Institute of Occupational Health, Helsinki.
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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