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rdf:type |
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lifeskim:mentions |
umls-concept:C0019733,
umls-concept:C0030956,
umls-concept:C0034790,
umls-concept:C0036576,
umls-concept:C0042776,
umls-concept:C0086418,
umls-concept:C0162326,
umls-concept:C0332307,
umls-concept:C1515655,
umls-concept:C1704241,
umls-concept:C1704529
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pubmed:issue |
2
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pubmed:dateCreated |
2001-1-4
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pubmed:databankReference |
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pubmed:abstractText |
Using HLA-peptide tetrameric complexes, we isolated human T-cell lymphotrophic virus type 1 Tax peptide-specific CD8(+) T cells ex vivo. Antigen-specific amino acid motifs were identified in the T-cell receptor Vbeta CDR3 region of clonally expanded CD8(+) T cells. This result directly confirms the importance of the CDR3 region in determining the antigen specificity in vivo.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-10097126,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-10636490,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-10666215,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-11027480,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-2213510,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-3043226,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-6261256,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-6979048,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-7962528,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-8176227,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-8551623,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-8666949,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-8763995,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-8810254,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-8824178,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-8906788,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-9385560,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-9491999,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-9586631,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-9586632,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-9647259,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-9722914,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-9862696,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11134322-9973440
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1065-71
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:11134322-Amino Acid Motifs,
pubmed-meshheading:11134322-Amino Acid Sequence,
pubmed-meshheading:11134322-CD8-Positive T-Lymphocytes,
pubmed-meshheading:11134322-Complementarity Determining Regions,
pubmed-meshheading:11134322-Gene Products, tax,
pubmed-meshheading:11134322-HLA-A2 Antigen,
pubmed-meshheading:11134322-HTLV-I Infections,
pubmed-meshheading:11134322-Human T-lymphotropic virus 1,
pubmed-meshheading:11134322-Humans,
pubmed-meshheading:11134322-Molecular Sequence Data,
pubmed-meshheading:11134322-Receptors, Antigen, T-Cell, alpha-beta,
pubmed-meshheading:11134322-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2001
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pubmed:articleTitle |
In vivo selection of T-cell receptor junctional region sequences by HLA-A2 human T-cell lymphotropic virus type 1 Tax11-19 peptide complexes.
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pubmed:affiliation |
Departments of Immunology, Imperial College School of Medicine, St. Mary's Campus, London W2 1PG, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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