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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2000-12-20
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pubmed:abstractText |
Bordetella pertussis causing severe respiratory failure in infants that is unresponsive to treatment is well described. Pulmonary hypertension is a prominent feature of such cases. In this series of 13 critically ill infants with B. pertussis, hyperleukocytosis ( > 100 x 10(9)/l) was an independent predictor of death. We suggest that such extreme leukocytosis may contribute to disease severity via the formation of aggregates in the pulmonary vasculature.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0342-4642
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1512-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11126265-Blood Gas Analysis,
pubmed-meshheading:11126265-Critical Illness,
pubmed-meshheading:11126265-Humans,
pubmed-meshheading:11126265-Hypertension, Pulmonary,
pubmed-meshheading:11126265-Infant,
pubmed-meshheading:11126265-Infant, Newborn,
pubmed-meshheading:11126265-Intensive Care, Neonatal,
pubmed-meshheading:11126265-Length of Stay,
pubmed-meshheading:11126265-Leukocyte Count,
pubmed-meshheading:11126265-Leukocytosis,
pubmed-meshheading:11126265-Logistic Models,
pubmed-meshheading:11126265-Lymphocyte Count,
pubmed-meshheading:11126265-Lymphocyte Subsets,
pubmed-meshheading:11126265-Predictive Value of Tests,
pubmed-meshheading:11126265-Pulmonary Circulation,
pubmed-meshheading:11126265-Respiratory Insufficiency,
pubmed-meshheading:11126265-Retrospective Studies,
pubmed-meshheading:11126265-Severity of Illness Index,
pubmed-meshheading:11126265-Survival Analysis,
pubmed-meshheading:11126265-Treatment Outcome,
pubmed-meshheading:11126265-Whooping Cough
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pubmed:year |
2000
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pubmed:articleTitle |
Is leukocytosis a predictor of mortality in severe pertussis infection?
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pubmed:affiliation |
Paediatric Intensive Care Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK.
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pubmed:publicationType |
Journal Article
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