11125216

Source:http://linkedlifedata.com/resource/pubmed/id/11125216

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0439799, umls-concept:C0449911, umls-concept:C0747055
pubmed:issue	5-6
pubmed:dateCreated	2001-1-26
pubmed:abstractText	Cells respond to osmotic swelling by releasing inorganic ions and small organic molecules (organic osmolytes). In many cell-types, osmotic swelling results in the activation of an outwardly-rectifying anion-selective current. The channel underlying this current has a significant permeability to a number of organic osmolytes and may play a role in the hypoosmotically-activated efflux of these compounds. However, there is also evidence that the volume-regulatory efflux of organic osmolytes involves other pathways which may be selective for neutral osmolytes over anions.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9113221
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Organic Chemicals
pubmed:status	MEDLINE
pubmed:issn	1015-8987
pubmed:author	pubmed-author:JunankarP RPR, pubmed-author:KirkKK
pubmed:copyrightInfo	Copyright 2000 S. Karger AG, Basel.
pubmed:issnType	Print
pubmed:volume	10
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	355-60
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:11125216-Animals, pubmed-meshheading:11125216-Organic Chemicals, pubmed-meshheading:11125216-Osmotic Pressure
pubmed:year	2000
pubmed:articleTitle	Organic osmolyte channels: a comparative view.
pubmed:affiliation	Division of Biochemistry and Molecular Biology, Faculty of Science, The Australian National University, Canberra, Australia.
pubmed:publicationType	Journal Article, Comparative Study, Review, Research Support, Non-U.S. Gov't