Linked Life Data

1112253

Source:http://linkedlifedata.com/resource/pubmed/id/1112253

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1975-5-6
pubmed:abstractText
The effect of dietary vitamin D levels on the response to iv injected parathyroid hormone (PTH) was studies in chicks fed one of three diets: D-deficient, Control-D (1.4IU cholecalciferol/g diet), or High-D (70 IU cholecalciferol/g diet) during the first 4 weeks post-hatching. Compared to chicks on Control-D diet, chicks on the D-deficient diet had significantly decreased plasma Ca levels at 2 and 4 weeks and increased plasma P levels at 17 and 21 days. The plasma Ca response to a low dose of PTH (15 USP U/100 g body wt) 1 hr postinjection was normal at 1 week, reduced at 2 weeks and absent at 4 weeks in D-deficient chicks. However, a 4-16-fold higher dose of PTH did elicit a significant, though subnormal, response in this group at 3 and 4 weeks. Chicks fed the D-deficient diet with 2.8% Ca, compared to 1.4% Ca, showed a near normal plasma Ca level and bone ash content and only a small increase in plasma P at 17 and 21 days. However, the plasma Ca response to 15 U PTH/100 g body wt in this group was significantly increased only at 17 days and not at 21 days. In contrast, the hyperphosphatemic response to PTH was not markedly diminished in the D-deficient group, and it was restored to Control-D levels in the D-deficienyt High Ca group. These data suggest that different mechanisms may be involved in the Ca and P responses.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0013-7227
pubmed:author
pubmed:issnType
Print
pubmed:volume
96
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
275-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Vitamin D, dietary calcium and parathyroid hormone interactions in chicks.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.