Linked Life Data

11121743

Source:http://linkedlifedata.com/resource/pubmed/id/11121743

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2000-12-27
pubmed:abstractText
The growth of pollen tubes to plant egg cells and the guidance of axons to neural synapses are classic examples of targeted cell growth. Despite the evolutionary time that separates animals and plants, axon and pollen tube guidance share remarkable mechanistic similarities. In both instances, extracellular cues are transduced by intracellular signal-transduction pathways that culminate in directed tip growth. Do the mechanistic similarities extend to the molecular level? Here, we address this question by a comprehensive review of the molecules and pathways involved in pollen tube targeting and axon guidance. The emerging scenario is that similar intracellular molecules are recruited to control tip growth, while different extracellular molecules mediate guidance through the distinct plant and animal extracellular matrices.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0962-8924
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
517-24
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Pollen tube targeting and axon guidance: parallels in tip growth mechanisms.
pubmed:affiliation
Howard Hughes Medical Institute, Dept of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL 60637, USA.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't