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pubmed-article:11106096pubmed:abstractTextIt has been suggested that a diminished folate status may enhance colorectal carcinogenesis by causing DNA hypomethylation. The aims of the present study were to assess the impact of different levels of folate depletion on azoxymethane (AOM)-induced aberrant crypt foci (ACF) formation and DNA hypomethylation in the colon of male Sprague-Dawley rats.lld:pubmed
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pubmed-article:11106096pubmed:articleTitleFolate deficiency diminishes the occurrence of aberrant crypt foci in the rat colon but does not alter global DNA methylation status.lld:pubmed
pubmed-article:11106096pubmed:affiliationUniversity of Adelaide, Department of Medicine, tCSIRO, Health Sciences and Nutrition, South Australia, Australia. richard.leleu@dhn.csiro.aulld:pubmed
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