Linked Life Data

11087906

Source:http://linkedlifedata.com/resource/pubmed/id/11087906

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-3
pubmed:dateCreated
2001-3-8
pubmed:abstractText
The effects of age on the dendritic tree of reduced nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d)-positive neurons in the dorsolateral neuronal column of the periaqueductal gray (DLPAG) in the rat were examined, using NADPH-d histochemistry and computer-assisted analysis. In 26-month-old rats some of the neurons exhibited considerably branched dendrites, while others show amputation stumps, or local swellings in the initial dendritic portion. Quantitative analysis demonstrated that the number of dendritic segments in DLPAG increased with advancing age. The mean segment length and the mean length of the terminal segment significantly increased in 12-month-old rats compared to 3-month-old rats and decreased in 26-month-old rats in comparison to 12-month-old, as the reduction was significant for the terminal segments only. The total dendritic length of NADPH-d-stained neurons increased with aging. The increase was more pronounced in 12-month-old rats compared to 3-month-old rats and the difference was significant in 26-month-old rats. The number of the nodal vertices, Va and Vb, significantly increased between 12- and 26-month of age. The dendritic reorganization was considered a sign of compensatory mechanism counteracting the degenerative changes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0047-6374
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
120
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
77-86
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Age-related changes in the NADPH-diaphorase-positive dendrites in the dorsolateral neuronal column of the periaqueductal gray in rat.
pubmed:affiliation
Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences, 73 Tzarigradsko shousse, 1113, Sofia, Bulgaria.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't