Source:http://linkedlifedata.com/resource/pubmed/id/11084207
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2000-12-8
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pubmed:abstractText |
Amperometry is a widely used technique for monitoring the secretion of catecholamines (CA) by exocytosis. The use of carbon fibre microelectrodes allows the on-line recording of CA released from a single secretory vesicle. Amperometric signals are generated by oxidation of the quantally released CA close to the electrode tip. Each event of exocytosis is called a secretory spike. Here we describe a program written for IGOR (Wavemetrics, Lake Oswego, OR, USA), which may be used to analyze amperometric signals off-line. The procedures allow, (i) digital filtering and analysis of the current noise, spike identification and calculation of spike kinetic parameters; (ii) spike review; (iii) pooling spikes and data to create galleries, tables and histograms of measured parameters which can be exported to a graphic format or files for further analysis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0165-0270
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
151-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11084207-Action Potentials,
pubmed-meshheading:11084207-Adrenal Medulla,
pubmed-meshheading:11084207-Algorithms,
pubmed-meshheading:11084207-Animals,
pubmed-meshheading:11084207-Catecholamines,
pubmed-meshheading:11084207-Cattle,
pubmed-meshheading:11084207-Chromaffin Cells,
pubmed-meshheading:11084207-Electrophysiology,
pubmed-meshheading:11084207-Exocytosis,
pubmed-meshheading:11084207-Microelectrodes,
pubmed-meshheading:11084207-Models, Neurological,
pubmed-meshheading:11084207-Secretory Vesicles,
pubmed-meshheading:11084207-Software
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pubmed:year |
2000
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pubmed:articleTitle |
Automatic analysis for amperometrical recordings of exocytosis.
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pubmed:affiliation |
Unidad de Farmacología, Facultad de Medicina, Universidad de La Laguna, Tenerife, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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