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rdf:type |
|
|
lifeskim:mentions |
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|
pubmed:issue |
5
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pubmed:dateCreated |
2000-12-26
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|
pubmed:abstractText |
We used flow cytometry to measure the activities of cathepsin G and elastase. The activity of elastase in neutrophils from patients with myelodysplastic syndrome (MDS) was significantly lower than that in neutrophils from the control group (P<.001). Patients with low elastase activity were significantly susceptible to infection (P<. 05). Our study suggests that analyzing antibacterial enzymes is useful in evaluating the prognosis of patients with MDS.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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|
pubmed:issn |
1058-4838
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
31
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1292-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11073768-Acute Disease,
pubmed-meshheading:11073768-Adult,
pubmed-meshheading:11073768-Aged,
pubmed-meshheading:11073768-Aged, 80 and over,
pubmed-meshheading:11073768-Cathepsin G,
pubmed-meshheading:11073768-Cathepsins,
pubmed-meshheading:11073768-Female,
pubmed-meshheading:11073768-Humans,
pubmed-meshheading:11073768-Leukemia, Myeloid,
pubmed-meshheading:11073768-Male,
pubmed-meshheading:11073768-Middle Aged,
pubmed-meshheading:11073768-Myelodysplastic Syndromes,
pubmed-meshheading:11073768-Neutrophils,
pubmed-meshheading:11073768-Pancreatic Elastase,
pubmed-meshheading:11073768-Prognosis,
pubmed-meshheading:11073768-Serine Endopeptidases,
pubmed-meshheading:11073768-Survival Analysis
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|
pubmed:year |
2000
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|
pubmed:articleTitle |
Decline in antibiotic enzyme activity of neutrophils is a prognostic factor for infections in patients with myelodysplastic syndrome.
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pubmed:affiliation |
First Department of Internal Medicine, Tokyo Medical University, Japan. yito@tokyo-med.ac.jp
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pubmed:publicationType |
Journal Article
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