| pubmed-article:11060053 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11060053 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:11060053 | lifeskim:mentions | umls-concept:C0033011 | lld:lifeskim |
| pubmed-article:11060053 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:11060053 | lifeskim:mentions | umls-concept:C0202081 | lld:lifeskim |
| pubmed-article:11060053 | lifeskim:mentions | umls-concept:C0040557 | lld:lifeskim |
| pubmed-article:11060053 | lifeskim:mentions | umls-concept:C1427559 | lld:lifeskim |
| pubmed-article:11060053 | lifeskim:mentions | umls-concept:C1442155 | lld:lifeskim |
| pubmed-article:11060053 | lifeskim:mentions | umls-concept:C0439661 | lld:lifeskim |
| pubmed-article:11060053 | lifeskim:mentions | umls-concept:C0600324 | lld:lifeskim |
| pubmed-article:11060053 | lifeskim:mentions | umls-concept:C0332185 | lld:lifeskim |
| pubmed-article:11060053 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:11060053 | pubmed:dateCreated | 2000-11-17 | lld:pubmed |
| pubmed-article:11060053 | pubmed:abstractText | We examined the efficiency of detection of immunoglobulin M (IgM) antibodies to a 35-kDa antigen (P35) of Toxoplasma gondii for serodiagnosis of acute infection in pregnant women. A double-sandwich enzyme-linked immunosorbent assay (ELISA) with recombinant P35 antigen (P35-IgM-ELISA) was used for this purpose. On the basis of the clinical history and the combination of results from the toxoplasma serological profile (Sabin-Feldman dye test, conventional IgM and IgA ELISAs, and the differential agglutination test), the patients were classified into three groups: group I, status suggestive of recently acquired infection; group II, status suggestive of infection acquired in the distant past; group III, status suggestive of persisting IgM antibodies. Eighteen (90.0%) of 20 serum samples from group I patients were positive by the P35-IgM-ELISA, whereas none of the 33 serum samples from group II patients were positive. Only 4 (25.0%) of 16 serum samples from group III patients were positive by the P35-IgM-ELISA, whereas all these serum samples were positive by the conventional IgM ELISA. These results indicate that demonstration of IgM antibodies against P35 by the P35-IgM-ELISA is more specific for the acute stage of the infection than demonstration of IgM antibodies by the ELISA that uses a whole-lysate antigen preparation. Studies with sera obtained from four pregnant women who seroconverted (IgG and IgM antibodies) during pregnancy revealed that two of them became negative by the P35-IgM-ELISA between 4 and 6 months after seroconversion, whereas the conventional IgM ELISA titers remained highly positive. The P35-IgM-ELISA appears to be useful for differentiating recently acquired infection from those acquired in the distant past in pregnant women. | lld:pubmed |
| pubmed-article:11060053 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11060053 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11060053 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11060053 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11060053 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:11060053 | pubmed:issn | 0095-1137 | lld:pubmed |
| pubmed-article:11060053 | pubmed:author | pubmed-author:SuzukiYY | lld:pubmed |
| pubmed-article:11060053 | pubmed:author | pubmed-author:LUGG | lld:pubmed |
| pubmed-article:11060053 | pubmed:author | pubmed-author:RamirezRR | lld:pubmed |
| pubmed-article:11060053 | pubmed:author | pubmed-author:RemingtonJ... | lld:pubmed |
| pubmed-article:11060053 | pubmed:author | pubmed-author:ThulliezPP | lld:pubmed |
| pubmed-article:11060053 | pubmed:author | pubmed-author:PrestDD | lld:pubmed |
| pubmed-article:11060053 | pubmed:author | pubmed-author:ParmleySS | lld:pubmed |
| pubmed-article:11060053 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11060053 | pubmed:volume | 38 | lld:pubmed |
| pubmed-article:11060053 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11060053 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11060053 | pubmed:pagination | 3967-70 | lld:pubmed |
| pubmed-article:11060053 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:meshHeading | pubmed-meshheading:11060053... | lld:pubmed |
| pubmed-article:11060053 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:11060053 | pubmed:articleTitle | Detection of immunoglobulin M antibodies to P35 antigen of Toxoplasma gondii for serodiagnosis of recently acquired infection in pregnant women. | lld:pubmed |
| pubmed-article:11060053 | pubmed:affiliation | Department of Immunology and Infectious Diseases, Research Institute, Palo Alto Medical Foundation, Palo Alto, California 94301, USA. ysuzuki@leland.stanford.edu | lld:pubmed |
| pubmed-article:11060053 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11060053 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:11060053 | pubmed:publicationType | Evaluation Studies | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11060053 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11060053 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11060053 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11060053 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11060053 | lld:pubmed |
