Linked Life Data

11055180

Source:http://linkedlifedata.com/resource/pubmed/id/11055180

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2000-12-5
pubmed:abstractText
This article discusses biochemical changes of ethyl alcohol in human organism, concentrating especially on the negative influence on the metabolism of liver. The authors describe the process of oxidation of alcohol with alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) and emphasize the role of ADH i ALDH isoenzymes in creating individual tolerance of ethanol. Two other ways of ethanol metabolism are also presented. These are: microsomal ethanol oxidation system (MEOS) connected with cytochrome P-450 and peroxisome catalase system. The article also describes the influence of alcohol and its products of metabolism on the structure of liver proteins, on different metabolic processes taking place in this organ, and on the changes in the immunological system in the course of the alcoholic liver disease. Moreover, the authors present some information about the changes in histopathological picture of liver as the result of alcohol abuse.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0033-2674
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
411-21
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Alcoholism: biology].
pubmed:affiliation
Kliniki Chorób Psychicznych-Akademia Medyczna w Bia?ymstoku.
pubmed:publicationType
Journal Article, English Abstract, Review