| pubmed-article:11045719 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11045719 | lifeskim:mentions | umls-concept:C1123023 | lld:lifeskim |
| pubmed-article:11045719 | lifeskim:mentions | umls-concept:C0013604 | lld:lifeskim |
| pubmed-article:11045719 | lifeskim:mentions | umls-concept:C0034286 | lld:lifeskim |
| pubmed-article:11045719 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:11045719 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:11045719 | pubmed:dateCreated | 2000-10-24 | lld:pubmed |
| pubmed-article:11045719 | pubmed:abstractText | The induction of edema and pyrimidine dimers in epidermal DNA was determined in the skin of SKH:HR1 mice exposed to graded doses of ultraviolet radiation AI (UVAI; 340-400 nm). Exposure to UVAI induced 1.6 +/- 0.08 x 10(-6) (mean +/- standard error of mean) pyrimidine dimers per 10(8) Da of DNA per J/m2. Edema in irradiated animals was determined as an increase in skinfold thickness. A dose of 1.8 x 10(6) J/m2 of UVAI that resulted in a 50% increase in skinfold thickness (SFT50%) would have induced 1.0 x 10(5) dimers per basal cell genome. A similar increase in SFT induced by full spectrum solar ultraviolet radiation (290-400 nm) would accompany the induction of 11.0 x 10(5) pyrimidine dimers per basal cell genome. These results support a hypothesis that UVAI-induced pathological changes of the skin are mediated through the formation of nondimer photoproducts. | lld:pubmed |
| pubmed-article:11045719 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11045719 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11045719 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11045719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11045719 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11045719 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11045719 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:11045719 | pubmed:issn | 0031-8655 | lld:pubmed |
| pubmed-article:11045719 | pubmed:author | pubmed-author:FourtanierAA | lld:pubmed |
| pubmed-article:11045719 | pubmed:author | pubmed-author:NEWP FPF | lld:pubmed |
| pubmed-article:11045719 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11045719 | pubmed:volume | 72 | lld:pubmed |
| pubmed-article:11045719 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11045719 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11045719 | pubmed:pagination | 485-7 | lld:pubmed |
| pubmed-article:11045719 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:11045719 | pubmed:meshHeading | pubmed-meshheading:11045719... | lld:pubmed |
| pubmed-article:11045719 | pubmed:meshHeading | pubmed-meshheading:11045719... | lld:pubmed |
| pubmed-article:11045719 | pubmed:meshHeading | pubmed-meshheading:11045719... | lld:pubmed |
| pubmed-article:11045719 | pubmed:meshHeading | pubmed-meshheading:11045719... | lld:pubmed |
| pubmed-article:11045719 | pubmed:meshHeading | pubmed-meshheading:11045719... | lld:pubmed |
| pubmed-article:11045719 | pubmed:meshHeading | pubmed-meshheading:11045719... | lld:pubmed |
| pubmed-article:11045719 | pubmed:meshHeading | pubmed-meshheading:11045719... | lld:pubmed |
| pubmed-article:11045719 | pubmed:meshHeading | pubmed-meshheading:11045719... | lld:pubmed |
| pubmed-article:11045719 | pubmed:meshHeading | pubmed-meshheading:11045719... | lld:pubmed |
| pubmed-article:11045719 | pubmed:meshHeading | pubmed-meshheading:11045719... | lld:pubmed |
| pubmed-article:11045719 | pubmed:meshHeading | pubmed-meshheading:11045719... | lld:pubmed |
| pubmed-article:11045719 | pubmed:meshHeading | pubmed-meshheading:11045719... | lld:pubmed |
| pubmed-article:11045719 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:11045719 | pubmed:articleTitle | UVAI-induced edema and pyrimidine dimers in murine skin. | lld:pubmed |
| pubmed-article:11045719 | pubmed:affiliation | Department of Cell Biology and Physiology and the Cancer Research and Treatment Center, University of New Mexico Health Sciences Center, Albuquerque, NM 87131-5218, USA. | lld:pubmed |
| pubmed-article:11045719 | pubmed:publicationType | Journal Article | lld:pubmed |
