Source:http://linkedlifedata.com/resource/pubmed/id/11029151
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
2000-11-29
|
pubmed:abstractText |
Arthrogryposis multiplex congenita (AMC) is defined as nonprogressive congenital contractures that generally result from lack of fetal movement in utero. AMC is a feature of many congenital disorders caused by genetic, environmental, or other factors. One rare cause of AMC is maternal myasthenia gravis (MG). This is an autoimmune disorder, caused by antibodies to the nicotinic acetylcholine receptor (AChR), and resulting in weakness of voluntary muscles. In 10-15% of babies born to MG mothers, transient signs of MG are noted after placental transfer of anti-AChR antibodies. In a few cases, AMC predominates.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0040-3709
|
pubmed:author | |
pubmed:copyrightInfo |
Copyright 2000 Wiley-Liss, Inc.
|
pubmed:issnType |
Print
|
pubmed:volume |
62
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
332-41
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11029151-Animals,
pubmed-meshheading:11029151-Arthrogryposis,
pubmed-meshheading:11029151-Autoantibodies,
pubmed-meshheading:11029151-Embryonic and Fetal Development,
pubmed-meshheading:11029151-Female,
pubmed-meshheading:11029151-Humans,
pubmed-meshheading:11029151-Mice,
pubmed-meshheading:11029151-Myasthenia Gravis,
pubmed-meshheading:11029151-Pregnancy,
pubmed-meshheading:11029151-Receptors, Cholinergic
|
pubmed:year |
2000
|
pubmed:articleTitle |
Teratogen update: maternal myasthenia gravis as a cause of congenital arthrogryposis.
|
pubmed:affiliation |
Neurosciences Group, Department of Clinical Neurology, University of Oxford, Institute of Molecular Medicine, Oxford Radcliffe Hospital, OX3 9DS, United Kingdom.
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|