| pubmed-article:11017071 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11017071 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
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| pubmed-article:11017071 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:11017071 | pubmed:dateCreated | 2000-11-8 | lld:pubmed |
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| pubmed-article:11017071 | pubmed:abstractText | Type 2 or non-insulin-dependent diabetes mellitus (NIDDM) is the most common form of diabetes worldwide, affecting approximately 4% of the world's adult population. It is multifactorial in origin with both genetic and environmental factors contributing to its development. A genome-wide screen for type 2 diabetes genes carried out in Mexican Americans localized a susceptibility gene, designated NIDDM1, to chromosome 2. Here we describe the positional cloning of a gene located in the NIDDM1 region that shows association with type 2 diabetes in Mexican Americans and a Northern European population from the Botnia region of Finland. This putative diabetes-susceptibility gene encodes a ubiquitously expressed member of the calpain-like cysteine protease family, calpain-10 (CAPN10). This finding suggests a novel pathway that may contribute to the development of type 2 diabetes. | lld:pubmed |
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| pubmed-article:11017071 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11017071 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11017071 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:11017071 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11017071 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:11017071 | pubmed:issn | 1061-4036 | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:HorikawaYY | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:COLEL JLJ | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:HaraMM | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:OdaYY | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:ROT KTK | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:BogardusCC | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:CoxN JNJ | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:SchulzeJJ | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:MashimaHH | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:ConcannonPP | lld:pubmed |
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| pubmed-article:11017071 | pubmed:author | pubmed-author:BoerwinkleEE | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:PolonskyK SKS | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:HanisC LCL | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:ColillaSS | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:BaierL JLJ | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:HinokioYY | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:LindnerT HTH | lld:pubmed |
| pubmed-article:11017071 | pubmed:author | pubmed-author:YoshiuchiII | lld:pubmed |
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| pubmed-article:11017071 | pubmed:author | pubmed-author:SchwarzP EPE | lld:pubmed |
| pubmed-article:11017071 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11017071 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:11017071 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11017071 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11017071 | pubmed:pagination | 163-75 | lld:pubmed |
| pubmed-article:11017071 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:11017071 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:11017071 | pubmed:articleTitle | Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. | lld:pubmed |
| pubmed-article:11017071 | pubmed:affiliation | Howard Hughes Medical Institute, The University of Chicago, Chicago, Illinois, USA. | lld:pubmed |
| pubmed-article:11017071 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11017071 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:11017071 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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