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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
4
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pubmed:dateCreated |
2000-11-20
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pubmed:abstractText |
OKTcdr4a (IMUCLONE) is a humanized anti-CD4 IgG4 monoclonal antibody that retains the binding and in vitro immunosuppressive properties of the parent murine antibody. Psoriasis is a chronic disease for which treatment with multiple doses of monoclonal antibodies is likely to be required for adequate control.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0190-9622
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pubmed:author |
pubmed-author:GilleaudeauPP,
pubmed-author:GisoldiEE,
pubmed-author:GottliebA BAB,
pubmed-author:GrossmanRR,
pubmed-author:KruegerJ GJG,
pubmed-author:LebwohlMM,
pubmed-author:NeislerH MHM,
pubmed-author:PhillipsSS,
pubmed-author:SherrAA,
pubmed-author:ShirinSS,
pubmed-author:SingerGG,
pubmed-author:SolodkinaGG
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pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
595-604
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pubmed:dateRevised |
2011-8-2
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pubmed:meshHeading |
pubmed-meshheading:11004613-Adult,
pubmed-meshheading:11004613-Antibodies, Monoclonal,
pubmed-meshheading:11004613-Antigens, CD4,
pubmed-meshheading:11004613-Dose-Response Relationship, Drug,
pubmed-meshheading:11004613-Double-Blind Method,
pubmed-meshheading:11004613-Female,
pubmed-meshheading:11004613-Humans,
pubmed-meshheading:11004613-Immunoglobulin G,
pubmed-meshheading:11004613-Male,
pubmed-meshheading:11004613-Middle Aged,
pubmed-meshheading:11004613-Pilot Projects,
pubmed-meshheading:11004613-Psoriasis,
pubmed-meshheading:11004613-Severity of Illness Index
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pubmed:year |
2000
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pubmed:articleTitle |
Anti-CD4 monoclonal antibody treatment of moderate to severe psoriasis vulgaris: results of a pilot, multicenter, multiple-dose, placebo-controlled study.
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pubmed:affiliation |
Clinical Research Center, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA. gottliab@umdnj.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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