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rdf:type |
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lifeskim:mentions |
umls-concept:C0014597,
umls-concept:C0033684,
umls-concept:C0162610,
umls-concept:C0205111,
umls-concept:C0521458,
umls-concept:C1514873,
umls-concept:C1546857,
umls-concept:C1556066,
umls-concept:C1619636,
umls-concept:C1947906,
umls-concept:C2246294
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pubmed:issue |
18
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pubmed:dateCreated |
2000-10-25
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pubmed:abstractText |
Polarised trafficking of proteins is critical for normal expression of the epithelial phenotype, but its genetic control is not understood. The regulatory gene lin-26 is essential for normal epithelial differentiation in the nematode Caenorhabditis elegans. To identify potential effectors of lin-26, we characterised mutations that result in lin-26-like phenotypes. Here, we report the phenotypic and molecular analysis of one such mutant line, che-14.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0960-9822
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1098-107
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10996790-Amino Acid Motifs,
pubmed-meshheading:10996790-Animals,
pubmed-meshheading:10996790-Caenorhabditis elegans,
pubmed-meshheading:10996790-Caenorhabditis elegans Proteins,
pubmed-meshheading:10996790-Cell Polarity,
pubmed-meshheading:10996790-Cytoplasmic Vesicles,
pubmed-meshheading:10996790-DNA-Binding Proteins,
pubmed-meshheading:10996790-Ectoderm,
pubmed-meshheading:10996790-Epithelial Cells,
pubmed-meshheading:10996790-Exocytosis,
pubmed-meshheading:10996790-Helminth Proteins,
pubmed-meshheading:10996790-Microscopy, Electron,
pubmed-meshheading:10996790-Microscopy, Phase-Contrast,
pubmed-meshheading:10996790-Neurons,
pubmed-meshheading:10996790-Phenotype,
pubmed-meshheading:10996790-Plasmids,
pubmed-meshheading:10996790-Protein Transport,
pubmed-meshheading:10996790-Recombinant Fusion Proteins,
pubmed-meshheading:10996790-Sequence Deletion,
pubmed-meshheading:10996790-Sterols,
pubmed-meshheading:10996790-Transcription Factors
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pubmed:year |
2000
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pubmed:articleTitle |
CHE-14, a protein with a sterol-sensing domain, is required for apical sorting in C. elegans ectodermal epithelial cells.
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pubmed:affiliation |
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, BP163, 1 rue Laurent Fries, 67404, Illkirch, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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