Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2000-11-24
pubmed:abstractText
Metal transport from the cytosol to the vacuole is thought to be an important component of ion tolerance and of a plant's potential for use in phytoremediation. The Arabidopsis antiporter CAX2 (calcium exchanger 2) may be a key mediator of this process. CAX2 expression in yeast suppressed both Ca(2+) and Mn(2+) growth defects. A peptide-specific antibody to the antiporter reacted with a 39-kD protein from plant vacuolar membranes. Tobacco (Nicotiana tabacum) plants expressing CAX2 accumulated more Ca(2+), Cd(2+), and Mn(2+) and were more tolerant to elevated Mn(2+) levels. Expression of CAX2 in tobacco increased Cd(2+) and Mn(2+) transport in isolated root tonoplast vesicles. These results suggest that CAX2 has a broad substrate range and modulation of this transporter may be an important component of future strategies to improve plant ion tolerance.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-10198075, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-10219995, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-10394943, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-10406802, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-10455050, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-10559438, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-10637655, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-10681464, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-1384584, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-1392592, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-16668783, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-2546682, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-2693940, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-6326095, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-7588708, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-7784507, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-7823019, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-8509367, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-8531789, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-8626454, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-8628289, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-8643627, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-8668190, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-8710949, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-9238019, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-9407035, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-9407036, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-9566978, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-9634787, http://linkedlifedata.com/resource/pubmed/commentcorrection/10982428-9751787
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0032-0889
pubmed:author
pubmed:issnType
Print
pubmed:volume
124
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
125-33
pubmed:dateRevised
2010-9-14
pubmed:meshHeading
pubmed-meshheading:10982428-Antiporters, pubmed-meshheading:10982428-Arabidopsis, pubmed-meshheading:10982428-Biological Transport, Active, pubmed-meshheading:10982428-Blotting, Northern, pubmed-meshheading:10982428-Cadmium, pubmed-meshheading:10982428-Calcium, pubmed-meshheading:10982428-Calcium-Binding Proteins, pubmed-meshheading:10982428-Cation Transport Proteins, pubmed-meshheading:10982428-Cations, Divalent, pubmed-meshheading:10982428-Cells, Cultured, pubmed-meshheading:10982428-Cytosol, pubmed-meshheading:10982428-Electrophoresis, Polyacrylamide Gel, pubmed-meshheading:10982428-Manganese, pubmed-meshheading:10982428-Phenotype, pubmed-meshheading:10982428-Plants, Genetically Modified, pubmed-meshheading:10982428-Plants, Toxic, pubmed-meshheading:10982428-Tobacco, pubmed-meshheading:10982428-Vacuoles, pubmed-meshheading:10982428-Yeasts
pubmed:year
2000
pubmed:articleTitle
Expression of arabidopsis CAX2 in tobacco. Altered metal accumulation and increased manganese tolerance.
pubmed:affiliation
Baylor College of Medicine, Plant Physiology Group, United States Department of Agriculture/Agricultural Research Service Children's Nutrition Research Center, Houston, Texas 77030, USA. kendalh@bcm.tmc.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.