Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1975-10-21
pubmed:abstractText
The cause of pediatric diarrhea in Brazil was investigated with use of assays for toxigenic and invasive bacteria. Potential etiologic agents were identified in 31 of 40 consecutive children with diarrhea: toxigenic Escherichia coli or klebsiella in 20 patients (50 per cent); invasive Esch, coli or salmonella in four (10 per cent), and both toxigenic and invasive organisms in seven (18 per cent). Fecal leukocytes were present in nine of the 11 patients (82 per cent) with invasive pathogens. All 27 patients with toxigenic isolates had organisms that produced heat-labile cholera-like toxin; three patients had Esch. coli that also produced a heat-stable toxin. Among 20 controls without diarrhea there were no organisms that produced heat-labile toxin or tissue invasion, but there was one Esch. coli that produced only heat-stable toxin and one salmonella. In this pediatric population Esch. coli appears to cause most acute diarrheas due to toxigenic and invasive pathogenic mechanisms.
pubmed:keyword
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0028-4793
pubmed:author
pubmed:issnType
Print
pubmed:day
18
pubmed:volume
293
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
567-72
pubmed:dateRevised
2009-10-27
pubmed:meshHeading
pubmed-meshheading:1097914-Acute Disease, pubmed-meshheading:1097914-Animals, pubmed-meshheading:1097914-Biological Assay, pubmed-meshheading:1097914-Brazil, pubmed-meshheading:1097914-Child, pubmed-meshheading:1097914-Child, Preschool, pubmed-meshheading:1097914-Diarrhea, Infantile, pubmed-meshheading:1097914-Enterotoxins, pubmed-meshheading:1097914-Escherichia coli, pubmed-meshheading:1097914-Escherichia coli Infections, pubmed-meshheading:1097914-Feces, pubmed-meshheading:1097914-Female, pubmed-meshheading:1097914-Guinea Pigs, pubmed-meshheading:1097914-Hot Temperature, pubmed-meshheading:1097914-Humans, pubmed-meshheading:1097914-Infant, pubmed-meshheading:1097914-Infant, Newborn, pubmed-meshheading:1097914-Klebsiella, pubmed-meshheading:1097914-Klebsiella Infections, pubmed-meshheading:1097914-Leukocytes, pubmed-meshheading:1097914-Male, pubmed-meshheading:1097914-Mice, pubmed-meshheading:1097914-Rabbits, pubmed-meshheading:1097914-Salmonella, pubmed-meshheading:1097914-Salmonella Infections
pubmed:year
1975
pubmed:articleTitle
Role of toxigenic and invasive bacteria in acute diarrhea of childhood.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.