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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2000-9-6
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pubmed:abstractText |
Inbred LEW/N and F344/N rats respectively, are susceptible and relatively resistant to a broad range of inflammatory/autoimmune diseases. We recently identified a quantitative trait locus (QTL) on chromosome 10 that protects the F344/N rat from carrageenan-induced exudation in a dominant fashion. Angiotensin I-converting enzyme (ACE) is one of the candidate genes located in this QTL region that plays an important role in inflammation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1076-1551
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
319-31
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pubmed:dateRevised |
2008-11-20
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pubmed:meshHeading |
pubmed-meshheading:10949912-Amino Acid Sequence,
pubmed-meshheading:10949912-Amino Acid Substitution,
pubmed-meshheading:10949912-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:10949912-Animals,
pubmed-meshheading:10949912-Base Sequence,
pubmed-meshheading:10949912-Binding Sites,
pubmed-meshheading:10949912-Blotting, Western,
pubmed-meshheading:10949912-Carrageenan,
pubmed-meshheading:10949912-DNA Mutational Analysis,
pubmed-meshheading:10949912-Exudates and Transudates,
pubmed-meshheading:10949912-Inflammation,
pubmed-meshheading:10949912-Inhibitory Concentration 50,
pubmed-meshheading:10949912-Kinetics,
pubmed-meshheading:10949912-Lisinopril,
pubmed-meshheading:10949912-Lung,
pubmed-meshheading:10949912-Molecular Sequence Data,
pubmed-meshheading:10949912-Mutation, Missense,
pubmed-meshheading:10949912-Peptidyl-Dipeptidase A,
pubmed-meshheading:10949912-Quantitative Trait, Heritable,
pubmed-meshheading:10949912-Rats,
pubmed-meshheading:10949912-Rats, Inbred F344,
pubmed-meshheading:10949912-Rats, Inbred Lew,
pubmed-meshheading:10949912-Rats, Sprague-Dawley,
pubmed-meshheading:10949912-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:10949912-Solubility
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pubmed:year |
2000
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pubmed:articleTitle |
Exclusion of angiotensin I-converting enzyme as a candidate gene involved in exudative inflammatory resistance in F344/N rats.
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pubmed:affiliation |
Section on Neuroendocrine Immunology and Behavior, National Institutes of Health, Bethesda, Maryland, USA.
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pubmed:publicationType |
Journal Article
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