Linked Life Data

10936698

Source:http://linkedlifedata.com/resource/pubmed/id/10936698

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2000-9-21
pubmed:abstractText
Effects of non-weight-bearing (NWB) on morphological and metabolic properties of motoneurons innervating the soleus muscle, a postural muscle, were studied in young growing rats. The soma size and the activity of succinate dehydrogenase (SDH), a mitochondrial enzyme, were examined after hindlimb suspension. The hindlimb suspension began at 21 day of age and lasted for 3 week. The results were compared with 21- and 42-day-old controls. The soleus motoneurons were identified by using a fluorescent retrograde tracer, nuclear yellow. The histochemical SDH activity of soleus motoneurons was not modified during the postnatal growth and after the NWB condition. However, postnatal increases in the soma size and the total SDH activity (SDH activityxsoma size) were arrested by the NWB condition. The results indicate that the weight support activity imposed on soleus motor units would be important to postnatal increases in the soma size and the total SDH activity (i.e. mitochondria) of soleus motoneurons.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
290
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
145-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Non-weight-bearing condition arrests the morphological and metabolic changes of rat soleus motoneurons during postnatal growth.
pubmed:affiliation
Department of Child Education, Nakamura Gakuen University, 814-0198, Fukuoka, Japan. nakahi@cc.nakamura-u.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't