Linked Life Data

10928702

Source:http://linkedlifedata.com/resource/pubmed/id/10928702

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-11-9
pubmed:abstractText
The purpose of this study was to evaluate whether low-power laser biostimulation of the osteo-chondral lesions of the knee could by itself reduce repair healing time. Surgery was performed on eighteen rabbits; a bilateral osteo-chondral lesion of 2.5mm in diameter and 2mm depth was created in the femoral medial condyle with a drill. The left knee of each animal was treated intraoperatively using the diode Ga-Al-As laser (780nm) with the following parameters: 300 Joules/cm2, 1 Watts, 300 Hertz, 10 minutes; the right knee was left untreated, as control group. The animals were divided into three groups, A, B and C, according to the survival time after surgery, two, six and twelve weeks, respectively. The explants from the femoral condyles, either treated employing laser energy or left untreated, were examined histomorphometrically. Results after laser treatment showed faster healing of the lesion at week 2 (p=0.043) and an overall improvement in cellular morphology (p=0.044), while a more regular aspect of the osteocartilaginous tissue was observed at week 12 (p=0.004). A relationship between laser biostimulation properties and healing of the osteo-chondral defect has been demonstrated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1073-1199
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
321-36
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Osteochondral lesion repair of the knee in the rabbit after low-power diode Ga-Al-As laser biostimulation: an experimental study.
pubmed:affiliation
Dept of Experimental Surgery, Rizzoli Orthopaedic Institute Bologna, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't