Source:http://linkedlifedata.com/resource/pubmed/id/10928175
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3B
|
| pubmed:dateCreated |
2000-8-17
|
| pubmed:abstractText |
The purpose of this study was to evaluate the usefulness of positron emission tomography with 18F-2-deoxyglucose (FDG-PET) for the detection of malignant bone metastases, and to compare FDG-PET results with conventional technetium-99m methylene diophosphate (Tc-99m MDP) bone scan findings. Twenty-four patients (10 females, 14 males, ages: 39-71 years) with biopsy-proven malignancy and suspected bone metastases, underwent whole body FDG-PET and bone scan to detect bone metastases. Bone metastases were established in 39 discordant bone lesions by histopathological examination of biopsy samples, MRI/CT, and follow-up bone scan/FDG-PET findings showing progressively and extensively widespread bone lesions. A total of 98 bone lesions found on either FDG-PET or bone scan were evaluated For 39 bone lesions with discordant findings between FDG-PET and bone scan, histopathological examination, MRI/CT and follow-up bone scan/FDG-PET findings revealed 8 metastatic and 0 benign bone lesions with positive FDG-PET findings, not detected on bone scan. Eleven metastatic and 20 benign bone lesions with positive bone scan findings were not detected on FDG-PET. FDG-PET has a better specificity, but a lower sensitivity for detecting malignant bone metastases when compared with bone scan.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0250-7005
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
20
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
2189-92
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:10928175-Adult,
pubmed-meshheading:10928175-Aged,
pubmed-meshheading:10928175-Bone Diseases,
pubmed-meshheading:10928175-Bone Neoplasms,
pubmed-meshheading:10928175-Bone and Bones,
pubmed-meshheading:10928175-Breast Neoplasms,
pubmed-meshheading:10928175-Diagnosis, Differential,
pubmed-meshheading:10928175-Female,
pubmed-meshheading:10928175-Fluorodeoxyglucose F18,
pubmed-meshheading:10928175-Humans,
pubmed-meshheading:10928175-Lung Neoplasms,
pubmed-meshheading:10928175-Male,
pubmed-meshheading:10928175-Middle Aged,
pubmed-meshheading:10928175-Prostatic Neoplasms,
pubmed-meshheading:10928175-Radiopharmaceuticals,
pubmed-meshheading:10928175-Sensitivity and Specificity,
pubmed-meshheading:10928175-Technetium Tc 99m Medronate,
pubmed-meshheading:10928175-Tomography, Emission-Computed
|
| pubmed:articleTitle |
Comparison and discrepancy of 18F-2-deoxyglucose positron emission tomography and Tc-99m MDP bone scan to detect bone metastases.
|
| pubmed:affiliation |
Department of Nuclear Medicine, Taichung Veterans General Hospital, Taiwan. kao@vghtc.vghtc.gov.tw
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|