Source:http://linkedlifedata.com/resource/pubmed/id/10915089
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2000-9-26
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pubmed:abstractText |
The prevalence of malaria infection in 102 paired maternal-blood and umbilical cord-blood samples was assessed by microscopy and polymerase chain reaction (PCR) in a holoendemic area in Kenya. Plasmodium falciparum single-species infection was detected in maternal peripheral blood (3.4%), whereas microscopy indicated that no Plasmodium species were in cord blood. In contrast, maternal-blood samples showed a PCR prevalence of 48% for P. falciparum, 25% for P. malariae, and 24% for P. ovale, and cord-blood samples showed a PCR prevalence of 32%, 23%, and 21%, respectively. Although mothers with mixed-species infections were more likely to have offspring infected with mixed species, the specific malaria species were discordant in paired maternal- and cord-blood samples. Triple-species infections were observed in 11 cord- and maternal-blood samples at a 5.5-fold greater frequency than expected. These findings indicate that Plasmodium species infections in cord blood are common, occur at lower densities, and may be acquired before parturition.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
182
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
558-63
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10915089-Adolescent,
pubmed-meshheading:10915089-Animals,
pubmed-meshheading:10915089-Base Sequence,
pubmed-meshheading:10915089-Child,
pubmed-meshheading:10915089-Endemic Diseases,
pubmed-meshheading:10915089-Female,
pubmed-meshheading:10915089-Fetal Blood,
pubmed-meshheading:10915089-Humans,
pubmed-meshheading:10915089-Infant, Newborn,
pubmed-meshheading:10915089-Kenya,
pubmed-meshheading:10915089-Malaria,
pubmed-meshheading:10915089-Molecular Sequence Data,
pubmed-meshheading:10915089-Plasmodium,
pubmed-meshheading:10915089-Plasmodium falciparum,
pubmed-meshheading:10915089-Plasmodium malariae,
pubmed-meshheading:10915089-Polymerase Chain Reaction,
pubmed-meshheading:10915089-Prevalence,
pubmed-meshheading:10915089-Sequence Homology, Nucleic Acid
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pubmed:year |
2000
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pubmed:articleTitle |
Frequent umbilical cord-blood and maternal-blood infections with Plasmodium falciparum, P. malariae, and P. ovale in Kenya.
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pubmed:affiliation |
Division of Geographic Medicine, Department of Medicine, Case Western Reserve University, Cleveland, Ohio 44106-4983, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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