Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1975-5-17
pubmed:abstractText
Multinucleate giant cells were collected by subcutaneous implantation of plastic films into mice. The attached cells were challanged in vitro with staphylococci, yeasts and sheep erythrocytes treated with either glutaraldehyde or isologous or heterologous antiserum. Cells containing more than seven nuclei rarely phagocytized yeasts or staphylococci, and the uptake and ingestion of sheep erythrocytes treated with heterologous antiserum was equally infrequent. Many sheep erythrocytes treated with isologous antiserum or glutaraldehyde attached to giant cells. When the adherent erythrocytes were related to the increased size of the multinucleate cell by dividing the number attaching by the number of nuclei in the giant cell, a progressive relative reduction was demonstrated as the nuclear content increased. It is suggested that these phenomena are due to the loss of surface receptors subsequent to fusion during the formation of multinucleate cells.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0002-9440
pubmed:author
pubmed:issnType
Print
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
343-58
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
An analysis of the Phagocytic potential of multinucleate foreign body giant cells.
pubmed:publicationType
Journal Article