Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:10899285rdf:typepubmed:Citationlld:pubmed
pubmed-article:10899285lifeskim:mentionsumls-concept:C0040995lld:lifeskim
pubmed-article:10899285lifeskim:mentionsumls-concept:C0038585lld:lifeskim
pubmed-article:10899285lifeskim:mentionsumls-concept:C0030685lld:lifeskim
pubmed-article:10899285lifeskim:mentionsumls-concept:C0392747lld:lifeskim
pubmed-article:10899285lifeskim:mentionsumls-concept:C0680255lld:lifeskim
pubmed-article:10899285lifeskim:mentionsumls-concept:C0391871lld:lifeskim
pubmed-article:10899285lifeskim:mentionsumls-concept:C1283071lld:lifeskim
pubmed-article:10899285lifeskim:mentionsumls-concept:C1963578lld:lifeskim
pubmed-article:10899285lifeskim:mentionsumls-concept:C0443172lld:lifeskim
pubmed-article:10899285lifeskim:mentionsumls-concept:C0205225lld:lifeskim
pubmed-article:10899285lifeskim:mentionsumls-concept:C1515655lld:lifeskim
pubmed-article:10899285pubmed:issue2lld:pubmed
pubmed-article:10899285pubmed:dateCreated2000-10-4lld:pubmed
pubmed-article:10899285pubmed:abstractTextSubstance P (SP) is synthesized in a subset of nociceptive sensory neurons and is released from their peripheral and central terminals. Here we demonstrate with the use of in vivo microdialysis and radioimmunoassay techniques that SP is also released within trigeminal ganglia following intraganglionic application of KCl, veratridine or capsaicin, and after electrical stimulation of peripheral afferent fibers. Both the basal and KCl-evoked release of SP are shown to be dependent on extracellular calcium. Using the turpentine-induced model of unilateral orofacial inflammation we also show that both the basal and KCl-evoked release of SP within trigeminal ganglia are greatly increased on the inflamed side 48 h after induction of inflammation. Coupled with previous demonstrations of excitatory effects of SP on sensory neurons, these results suggest that SP fulfils the role of a non-synaptically released diffusible chemical messenger that may modulate the somatic excitability of neurons within sensory ganglia in inflammatory pain states.lld:pubmed
pubmed-article:10899285pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10899285pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10899285pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10899285pubmed:languageenglld:pubmed
pubmed-article:10899285pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10899285pubmed:citationSubsetIMlld:pubmed
pubmed-article:10899285pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10899285pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10899285pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10899285pubmed:statusMEDLINElld:pubmed
pubmed-article:10899285pubmed:monthJullld:pubmed
pubmed-article:10899285pubmed:issn0006-8993lld:pubmed
pubmed-article:10899285pubmed:authorpubmed-author:KrugerLLlld:pubmed
pubmed-article:10899285pubmed:authorpubmed-author:MatsukaYYlld:pubmed
pubmed-article:10899285pubmed:authorpubmed-author:SpigelmanIIlld:pubmed
pubmed-article:10899285pubmed:authorpubmed-author:MaidmentN TNTlld:pubmed
pubmed-article:10899285pubmed:authorpubmed-author:AdelsonD WDWlld:pubmed
pubmed-article:10899285pubmed:authorpubmed-author:NeubertJ KJKlld:pubmed
pubmed-article:10899285pubmed:issnTypePrintlld:pubmed
pubmed-article:10899285pubmed:day21lld:pubmed
pubmed-article:10899285pubmed:volume871lld:pubmed
pubmed-article:10899285pubmed:ownerNLMlld:pubmed
pubmed-article:10899285pubmed:authorsCompleteYlld:pubmed
pubmed-article:10899285pubmed:pagination181-91lld:pubmed
pubmed-article:10899285pubmed:dateRevised2007-11-14lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:meshHeadingpubmed-meshheading:10899285...lld:pubmed
pubmed-article:10899285pubmed:year2000lld:pubmed
pubmed-article:10899285pubmed:articleTitleInflammation-induced changes in primary afferent-evoked release of substance P within trigeminal ganglia in vivo.lld:pubmed
pubmed-article:10899285pubmed:affiliationDivision of Oral Biology and Medicine, UCLA School of Dentistry, 90095-1668, Los Angeles, CA, USA.lld:pubmed
pubmed-article:10899285pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10899285pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:10899285pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10899285lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10899285lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10899285lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10899285lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10899285lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10899285lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10899285lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10899285lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10899285lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10899285lld:pubmed