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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2000-9-1
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pubmed:abstractText |
A diagnostic examination for short stature in a boy with chronic ulcers of the feet due to prolidase deficiency, a rare disorder associated with intractable ulcers of the skin, led to the diagnosis of growth hormone (GH) deficiency. Replacement treatment with r-hGH associated with the topical application of a GH-containing ointment when the boy was 13 years old resulted in complete but transitory healing of the ulcers, which can probably be attributed to the growth-promoting effects of GH on dermal connective tissue.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:issn |
0736-8046
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pubmed:author |
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|
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
227-30
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pubmed:dateRevised |
2009-3-3
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pubmed:meshHeading |
pubmed-meshheading:10886759-Adolescent,
pubmed-meshheading:10886759-Child,
pubmed-meshheading:10886759-Dipeptidases,
pubmed-meshheading:10886759-Foot Ulcer,
pubmed-meshheading:10886759-Growth Hormone,
pubmed-meshheading:10886759-Hormone Replacement Therapy,
pubmed-meshheading:10886759-Humans,
pubmed-meshheading:10886759-Male,
pubmed-meshheading:10886759-Ointments,
pubmed-meshheading:10886759-Recombinant Proteins,
pubmed-meshheading:10886759-Skin Ulcer
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pubmed:articleTitle |
Transient beneficial effect of GH replacement therapy and topical GH application on skin ulcers in a boy with prolidase deficiency.
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pubmed:affiliation |
Department of Pediatric Sciences, IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy. gl.marseglia@smatteo.pv.it
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pubmed:publicationType |
Journal Article,
Case Reports
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